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KMID : 1101420180500030253
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Korean Journal of Clinical Laboratory Science
2018 Volume.50 No. 3 p.253 ~ p.260
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Distribution of the Fasting Lipid Levels and Validation of the Reference Interval in Korean Adolescents
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Kwon Se-Young
Ra Young-Ak
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Abstract
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With the growing prevalence of dyslipidemia in adolescents, its early detection and management is becoming increasingly important. This study overviewed the fasting lipid concentration distribution of adolescents according to the sex and age, and reviewed the percentile of its reference interval. This study targeted 2,713 adolescents aged between 10 and 19 (1,436 boys, 1,275 girls) based on the data from 2013 to 2016, Korean Health and Nutrition Examination Survey. The mean fasting lipid concentration of total cholesterol, LDL cholesterol, HDL cholesterol, non-HDL cholesterol, and triglyceride of girls was higher than those of boys. Although the 95th percentile of the cholesterol value was 200 mg/dL in boys, which was equivalent to the diagnosis criterion, the mean value of girls was 208 mg/dL, staying between the 90th and 95th percentiles. The 95th percentiles of the LDL cholesterol, non-HDL cholesterol, and triglyceride value were 123, 148, and 147 mg/dL in boys, respectively, and 131, 149, and 139 mg/dL in girls, respectively. Most of the criteria of dyslipidemia were at the proper level, within the 90th and 95th percentile. While the criteria of LDL cholesterol (130 mg/dL) was higher in boys, the triglycerides was higher in girls. In conclusion, criteria more suitable to Korean adolescents will need to be established with further studies.
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KEYWORD
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Criteria of dyslipidemia, Fasting lipid levels, Reference interval
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